中文名 | Diphenylterazine |
英文名 | Diphenylterazine |
别名 | 化合物DIPHENYLTERAZINE 2-苄基-6,8-二苯基咪唑并[1,2-A]吡嗪-3(7H)-酮 |
英文别名 | DTZ Diphenylterazine diphenylterazine Diphenylterazine (DTZ) 2-Benzyl-6,8-diphenylimidazo[1,2-a]pyrazin-3(7H)-one Imidazo[1,2-a]pyrazin-3(7H)-one, 6,8-diphenyl-2-(phenylmethyl)- |
CAS | 344940-63-2 |
化学式 | C25H19N3O |
分子量 | 377.44 |
密度 | 1.21±0.1 g/cm3(Predicted) |
沸点 | 538.4±60.0 °C(Predicted) |
酸度系数 | 6.33±0.40(Predicted) |
存储条件 | -20℃ |
体外研究 | Diphenylterazine elicits minimal cell toxicity at millimolar concentrations. Notes : To make a stock solution for DTZ (Diphenylterazine), first, a premixture is prepared by dissolving 17.6 mg of L-ascorbic acid (HY-B0166) in 10 mL ethanol and 10 mL 1,2-propanediol; next, 1 mg of DTZ is dissolved in 88 µL of the premix, resulting in a 30 mM DTZ stock solution containing 5 mM L-ascorbic acid. |
体内研究 | Diphenylterazine injections into untransfected BALB/c mice do not yield any background emission. The bioluminescence resulting from intraperitoneally injected Diphenylterazine displays extended kinetics. DTZ (0.3 μmol/mouse; i.v.) treatment can track tumor growth in a xenograft NU/J mouse model. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.649 ml | 13.247 ml | 26.494 ml |
5 mM | 0.53 ml | 2.649 ml | 5.299 ml |
10 mM | 0.265 ml | 1.325 ml | 2.649 ml |
5 mM | 0.053 ml | 0.265 ml | 0.53 ml |
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